I figured, or found out a few things on my car.
First thing is my Corvette style filter/regulator isn't regulating..
My fuel pressure at the rail is 100psi.
Another thing, Holley calls their tune files global configuration file, or GCF.
If I use the little 3.5" handheld touchscreen and wizard to build a base tune, it works, allows me to do the required tps reset but is much more basic.
If I use a GCF from the terminator x software off my laptop, there's much more I can do, but it fails the tps autoset every time.
So I used the handheld to create a baseline, then connected my laptop to modify it.
When I changed the actual fuel psi parameter from the 60psi baseline to 100, it still ran like garbage, but less garbage..
At this point I've pretty much decided I am going to pull the fuel tank, strip out all the lines and re-plumb the whole thing with AN lines and an adjustable regulator in the return.
While it's out, I will also need to cut the filler neck and extend it with a few inches of hose. Due to the pump, I had to shim the front of the tank and it puts the filler at a real pain in the aśş angle at the back bumper.