They can be made into a very strong and reliable power plant.
From a machinists perspective, all V8’s are just V8’s. Each brand has its different approach to how the heads are laid out, and that pretty much the only difference between them. 2 bolt, 4 bolt, doesn’t much matter at street power levels. They all run essentially the same. It’s just finding what each brand and series likes for the combination of head volume, and camshaft.
That being said, in the muscle era, obviously the big brands were racing to make the most power. It’s no secret that Mopar made more HP per cubic inch than any other V8 when they debuted the Hemi. Aside from that, they are all expensive to make high HP with. People used to argue that the SBC was the cheapest V8 to build. They weren’t wrong when talking about a budget build for the grocery getter. Once you start putting forged cranks and pistons etc into them for racing, they aren’t any cheaper. Pick what you want to run, and go with it.