Joe and 4P, loving the tech discussion. Right up my alley.
My opinion my be right or quite wrong.
I'm a relative novice in this game, but I've found that I don't use Blowdown as a basis of where I want transfers. I do look back at it, after my plan, to make sure something doesn't seem really off.
I kinda do it based on case volume, transfer shape and volume and intake closing points. Also port shape and design. I don't think any one rule fits any particular engine.
I find I like lower exhausts. If I can fill the cylinder with more charge, I can take advantage of more of the pressure it builds from combustion.
I believe physically higher (numerically lower) transfers build better high rpm power but sacrifice low end torque. I see the potential for some back stuffing at low rpm when charge inertia can't overcome it.
I do believe many very high factory transfer saws are that was because of a very restictive exhaust. They need more time to fill the cylinder because of the back pressure.
I do like to think of the plume shape exiting the transfers. In my minds eye, I want it to be fat and directional. I think opening the exhaust side first makes the ribbon of flow thicker. Quads give ya the best of both worlds, lots to play with there.
Sorry if I'm rambling a bit. I'm a port flow nerd.