Basically about 33% slower - but part of that will be compensated by less resistance in the wood (= higher chain speed). Part of it can be compensated by a larger drive sprocket as well, if the saw is strong enough - but then the resistance in the wood also goes up again.
There really is only one way to find the final answer, with a specific operator and saw, in specific wood - trying to calculate it is bound to fail...
I believe a good rule of thumb is to only use skip if chip clearance is the issue - not for any other (expected/theoretical) purpose - unless the saw just is too small and weak for the wood and/or bar length?