It kinda depends on where the screw stops adding fuel. Some quit at 1.5 turns. The rwj adds fuel until the screw gets sloppy at 4 turns. Just be careful drilling because it’s easy to go too far to where you can’t lean them out enough.
I’ve found that in “most” circumstances, feeling the need to drill jets is a bandaid to fix a different issue like weak impulse, plugged jets, or stiff diaphragms.
The faster flowing air of a ported or muff modded saw usually pulls more fuel through the main nozzle. Sometimes they need to be leaned out afterwards rather than richened